Does BUSULFAN Cause Thrombotic microangiopathy? 290 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 290 reports of Thrombotic microangiopathy have been filed in association with BUSULFAN (Busulfan). This represents 2.6% of all adverse event reports for BUSULFAN.
290
Reports of Thrombotic microangiopathy with BUSULFAN
2.6%
of all BUSULFAN reports
97
Deaths
51
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From BUSULFAN?
Of the 290 reports, 97 (33.4%) resulted in death, 51 (17.6%) required hospitalization, and 15 (5.2%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
Yes, Thrombotic microangiopathy is listed as a known adverse reaction in the official FDA drug label for BUSULFAN.
What Other Side Effects Does BUSULFAN Cause?
Off label use (1,402)
Product use in unapproved indication (1,387)
Mucosal inflammation (880)
Venoocclusive liver disease (765)
Febrile neutropenia (628)
Cytomegalovirus infection (620)
Drug ineffective (569)
Graft versus host disease (507)
Pyrexia (502)
Cytomegalovirus infection reactivation (481)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which BUSULFAN Alternatives Have Lower Thrombotic microangiopathy Risk?
BUSULFAN vs BUSULFEX
BUSULFAN vs BUTALBITAL
BUSULFAN vs BUTENAFINE
BUSULFAN vs BUTORPHANOL
BUSULFAN vs BUTRANS