Does CANAGLIFLOZIN Cause Off label use? 724 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 724 reports of Off label use have been filed in association with CANAGLIFLOZIN (INVOKANA). This represents 3.0% of all adverse event reports for CANAGLIFLOZIN.
724
Reports of Off label use with CANAGLIFLOZIN
3.0%
of all CANAGLIFLOZIN reports
15
Deaths
272
Hospitalizations
How Dangerous Is Off label use From CANAGLIFLOZIN?
Of the 724 reports, 15 (2.1%) resulted in death, 272 (37.6%) required hospitalization, and 31 (4.3%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CANAGLIFLOZIN. However, 724 reports have been filed with the FAERS database.
What Other Side Effects Does CANAGLIFLOZIN Cause?
Diabetic ketoacidosis (3,413)
Toe amputation (2,193)
Osteomyelitis (2,146)
Acute kidney injury (1,853)
Fungal infection (1,385)
Gangrene (1,081)
Weight decreased (1,014)
Cellulitis (1,007)
Urinary tract infection (920)
Diabetic foot infection (832)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which CANAGLIFLOZIN Alternatives Have Lower Off label use Risk?
CANAGLIFLOZIN vs CANAGLIFLOZIN\METFORMIN
CANAGLIFLOZIN vs CANAKINUMAB
CANAGLIFLOZIN vs CANDESARTAN
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL\HYDROCHLOROTHIAZIDE