Does CARBOPLATIN Cause Hypertransaminasaemia? 304 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 304 reports of Hypertransaminasaemia have been filed in association with CARBOPLATIN (Carboplatin). This represents 0.4% of all adverse event reports for CARBOPLATIN.
304
Reports of Hypertransaminasaemia with CARBOPLATIN
0.4%
of all CARBOPLATIN reports
12
Deaths
110
Hospitalizations
How Dangerous Is Hypertransaminasaemia From CARBOPLATIN?
Of the 304 reports, 12 (3.9%) resulted in death, 110 (36.2%) required hospitalization, and 12 (3.9%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CARBOPLATIN. However, 304 reports have been filed with the FAERS database.
What Other Side Effects Does CARBOPLATIN Cause?
Off label use (6,100)
Neutropenia (5,314)
Anaemia (5,312)
Febrile neutropenia (4,888)
Nausea (4,588)
Disease progression (4,538)
Thrombocytopenia (4,483)
Malignant neoplasm progression (4,177)
Diarrhoea (4,154)
Dyspnoea (3,494)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
RITUXIMAB (168)
Which CARBOPLATIN Alternatives Have Lower Hypertransaminasaemia Risk?
CARBOPLATIN vs CARBOPROST TROMETHAMINE
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE\GLYCERIN
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE\GLYCERIN\POLYSORBATE 80
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE\HYPROMELLOSES