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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hypertransaminasaemia: Which Medications Cause It? (5,646 Reports Across 465 Drugs)

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Hypertransaminasaemia has been reported as an adverse event with 465 different drugs in the FDA's FAERS database, with 5,646 total reports. 381 of these reports resulted in death.The drugs most commonly associated with Hypertransaminasaemia are METHOTREXATE, ACETAMINOPHEN, and PACLITAXEL.

5,646
Total Reports
465
Drugs Involved
381
Deaths
2,359
Hospitalizations
51.7 yrs
Average Patient Age
55.3% / 44.7%
Female / Male

Which Drugs Cause Hypertransaminasaemia Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
METHOTREXATE 436 0.2% 53 187 61
ACETAMINOPHEN 326 0.2% 13 199 50
PACLITAXEL 318 0.4% 3 94 12
CARBOPLATIN 304 0.4% 12 110 12
PEMBROLIZUMAB 231 0.3% 8 117 9
ATORVASTATIN 207 0.3% 19 91 36
CYCLOPHOSPHAMIDE 202 0.2% 12 84 20
PREDNISONE 198 0.1% 21 87 41
GEMCITABINE 196 0.6% 7 29 10
DEXAMETHASONE 169 0.1% 27 76 18
RITUXIMAB 168 0.1% 24 54 38
FLUOROURACIL 159 0.3% 2 16 2
DOXORUBICIN 149 0.2% 5 52 16
TOCILIZUMAB 148 0.2% 41 51 34
NIVOLUMAB 139 0.2% 15 53 9
OXALIPLATIN 139 0.3% 0 14 2
HYDROXYCHLOROQUINE 124 0.2% 26 56 40
VINCRISTINE 124 0.2% 9 71 13
PEMETREXED 122 0.5% 3 24 4
MYCOPHENOLATE MOFETIL 121 0.2% 22 39 44

View all 465 drugs →

Top 3 Drugs Associated With Hypertransaminasaemia

436 reports
326 reports
318 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)