Does TOCILIZUMAB Cause Hypertransaminasaemia? 148 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 148 reports of Hypertransaminasaemia have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.2% of all adverse event reports for TOCILIZUMAB.
148
Reports of Hypertransaminasaemia with TOCILIZUMAB
0.2%
of all TOCILIZUMAB reports
41
Deaths
51
Hospitalizations
How Dangerous Is Hypertransaminasaemia From TOCILIZUMAB?
Of the 148 reports, 41 (27.7%) resulted in death, 51 (34.5%) required hospitalization, and 34 (23.0%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 148 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which TOCILIZUMAB Alternatives Have Lower Hypertransaminasaemia Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE