Does PACLITAXEL Cause Hypertransaminasaemia? 318 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 318 reports of Hypertransaminasaemia have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.4% of all adverse event reports for PACLITAXEL.
318
Reports of Hypertransaminasaemia with PACLITAXEL
0.4%
of all PACLITAXEL reports
3
Deaths
94
Hospitalizations
How Dangerous Is Hypertransaminasaemia From PACLITAXEL?
Of the 318 reports, 3 (0.9%) resulted in death, 94 (29.6%) required hospitalization, and 12 (3.8%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 318 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
RITUXIMAB (168)
Which PACLITAXEL Alternatives Have Lower Hypertransaminasaemia Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON