Does FLUOROURACIL Cause Hypertransaminasaemia? 159 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 159 reports of Hypertransaminasaemia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.3% of all adverse event reports for FLUOROURACIL.
159
Reports of Hypertransaminasaemia with FLUOROURACIL
0.3%
of all FLUOROURACIL reports
2
Deaths
16
Hospitalizations
How Dangerous Is Hypertransaminasaemia From FLUOROURACIL?
Of the 159 reports, 2 (1.3%) resulted in death, 16 (10.1%) required hospitalization, and 2 (1.3%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 159 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which FLUOROURACIL Alternatives Have Lower Hypertransaminasaemia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE