Does CHLORAMBUCIL Cause Progressive multifocal leukoencephalopathy? 46 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 46 reports of Progressive multifocal leukoencephalopathy have been filed in association with CHLORAMBUCIL (LEUKERAN). This represents 2.0% of all adverse event reports for CHLORAMBUCIL.
46
Reports of Progressive multifocal leukoencephalopathy with CHLORAMBUCIL
2.0%
of all CHLORAMBUCIL reports
23
Deaths
19
Hospitalizations
How Dangerous Is Progressive multifocal leukoencephalopathy From CHLORAMBUCIL?
Of the 46 reports, 23 (50.0%) resulted in death, 19 (41.3%) required hospitalization, and 7 (15.2%) were considered life-threatening.
Is Progressive multifocal leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CHLORAMBUCIL. However, 46 reports have been filed with the FAERS database.
What Other Side Effects Does CHLORAMBUCIL Cause?
Off label use (176)
Neutropenia (173)
Pneumonia (158)
Pyrexia (132)
Acute myeloid leukaemia (107)
Disease progression (104)
Drug ineffective (103)
Febrile neutropenia (94)
Thrombocytopenia (93)
Myositis (89)
What Other Drugs Cause Progressive multifocal leukoencephalopathy?
NATALIZUMAB (1,668)
RITUXIMAB (1,647)
CYCLOPHOSPHAMIDE (782)
PREDNISONE (606)
PREDNISOLONE (439)
TACROLIMUS (438)
METHOTREXATE (428)
DOXORUBICIN (421)
MYCOPHENOLATE MOFETIL (414)
VINCRISTINE (376)
Which CHLORAMBUCIL Alternatives Have Lower Progressive multifocal leukoencephalopathy Risk?
CHLORAMBUCIL vs CHLORAMPHENICOL
CHLORAMBUCIL vs CHLORDIAZEPOXIDE
CHLORAMBUCIL vs CHLORDIAZEPOXIDE\CLIDINIUM
CHLORAMBUCIL vs CHLORHEXIDINE
CHLORAMBUCIL vs CHLORHEXIDINE\CHLORHEXIDINE