Does CISPLATIN Cause Hepatic necrosis? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Hepatic necrosis have been filed in association with CISPLATIN (CISplatin). This represents 0.1% of all adverse event reports for CISPLATIN.
28
Reports of Hepatic necrosis with CISPLATIN
0.1%
of all CISPLATIN reports
14
Deaths
5
Hospitalizations
How Dangerous Is Hepatic necrosis From CISPLATIN?
Of the 28 reports, 14 (50.0%) resulted in death, 5 (17.9%) required hospitalization, and 2 (7.1%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CISPLATIN. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does CISPLATIN Cause?
Off label use (4,359)
Disease progression (3,746)
Neutropenia (3,095)
Febrile neutropenia (3,010)
Nausea (2,923)
Drug ineffective (2,608)
Thrombocytopenia (2,565)
Anaemia (2,530)
Vomiting (2,326)
Diarrhoea (2,022)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which CISPLATIN Alternatives Have Lower Hepatic necrosis Risk?
CISPLATIN vs CISPLATIN\CYTARABINE\DEXAMETHASONE
CISPLATIN vs CITALOPRAM
CISPLATIN vs CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITALOPRAM\CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITICOLINE