Does CISPLATIN Cause Osteonecrosis? 46 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 46 reports of Osteonecrosis have been filed in association with CISPLATIN (CISplatin). This represents 0.1% of all adverse event reports for CISPLATIN.
46
Reports of Osteonecrosis with CISPLATIN
0.1%
of all CISPLATIN reports
8
Deaths
9
Hospitalizations
How Dangerous Is Osteonecrosis From CISPLATIN?
Of the 46 reports, 8 (17.4%) resulted in death, 9 (19.6%) required hospitalization, and 1 (2.2%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CISPLATIN. However, 46 reports have been filed with the FAERS database.
What Other Side Effects Does CISPLATIN Cause?
Off label use (4,359)
Disease progression (3,746)
Neutropenia (3,095)
Febrile neutropenia (3,010)
Nausea (2,923)
Drug ineffective (2,608)
Thrombocytopenia (2,565)
Anaemia (2,530)
Vomiting (2,326)
Diarrhoea (2,022)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which CISPLATIN Alternatives Have Lower Osteonecrosis Risk?
CISPLATIN vs CISPLATIN\CYTARABINE\DEXAMETHASONE
CISPLATIN vs CITALOPRAM
CISPLATIN vs CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITALOPRAM\CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITICOLINE