Does CLOFARABINE Cause Encephalopathy? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Encephalopathy have been filed in association with CLOFARABINE (Clofarabine). This represents 1.2% of all adverse event reports for CLOFARABINE.
17
Reports of Encephalopathy with CLOFARABINE
1.2%
of all CLOFARABINE reports
16
Deaths
5
Hospitalizations
How Dangerous Is Encephalopathy From CLOFARABINE?
Of the 17 reports, 16 (94.1%) resulted in death, 5 (29.4%) required hospitalization, and 1 (5.9%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOFARABINE. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does CLOFARABINE Cause?
Febrile neutropenia (201)
Off label use (158)
Drug ineffective (139)
Pyrexia (139)
Mucosal inflammation (89)
Sepsis (85)
Alanine aminotransferase increased (82)
Acute kidney injury (80)
Multiple organ dysfunction syndrome (77)
Aspartate aminotransferase increased (76)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which CLOFARABINE Alternatives Have Lower Encephalopathy Risk?
CLOFARABINE vs CLOFAZIMINE
CLOFARABINE vs CLOMETHIAZOLE
CLOFARABINE vs CLOMIPHENE
CLOFARABINE vs CLOMIPRAMINE
CLOFARABINE vs CLONAZEPAM