Does CLOFARABINE Cause Hepatic failure? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Hepatic failure have been filed in association with CLOFARABINE (Clofarabine). This represents 1.3% of all adverse event reports for CLOFARABINE.
19
Reports of Hepatic failure with CLOFARABINE
1.3%
of all CLOFARABINE reports
17
Deaths
3
Hospitalizations
How Dangerous Is Hepatic failure From CLOFARABINE?
Of the 19 reports, 17 (89.5%) resulted in death, 3 (15.8%) required hospitalization, and 9 (47.4%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOFARABINE. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does CLOFARABINE Cause?
Febrile neutropenia (201)
Off label use (158)
Drug ineffective (139)
Pyrexia (139)
Mucosal inflammation (89)
Sepsis (85)
Alanine aminotransferase increased (82)
Acute kidney injury (80)
Multiple organ dysfunction syndrome (77)
Aspartate aminotransferase increased (76)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which CLOFARABINE Alternatives Have Lower Hepatic failure Risk?
CLOFARABINE vs CLOFAZIMINE
CLOFARABINE vs CLOMETHIAZOLE
CLOFARABINE vs CLOMIPHENE
CLOFARABINE vs CLOMIPRAMINE
CLOFARABINE vs CLONAZEPAM