Does CLOZAPINE Cause Bone marrow failure? 73 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 73 reports of Bone marrow failure have been filed in association with CLOZAPINE (CLOZAPINE). This represents 0.1% of all adverse event reports for CLOZAPINE.
73
Reports of Bone marrow failure with CLOZAPINE
0.1%
of all CLOZAPINE reports
17
Deaths
31
Hospitalizations
How Dangerous Is Bone marrow failure From CLOZAPINE?
Of the 73 reports, 17 (23.3%) resulted in death, 31 (42.5%) required hospitalization, and 7 (9.6%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 73 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which CLOZAPINE Alternatives Have Lower Bone marrow failure Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL