Does CODEINE Cause Depression? 503 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 503 reports of Depression have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 2.3% of all adverse event reports for CODEINE.
503
Reports of Depression with CODEINE
2.3%
of all CODEINE reports
221
Deaths
260
Hospitalizations
How Dangerous Is Depression From CODEINE?
Of the 503 reports, 221 (43.9%) resulted in death, 260 (51.7%) required hospitalization, and 209 (41.6%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for CODEINE.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which CODEINE Alternatives Have Lower Depression Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE