Does CODEINE Cause Hepatic necrosis? 13 Reports in FDA Database
Grow Your Own Natural Pharmacy at Home
Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.
According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hepatic necrosis have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 0.1% of all adverse event reports for CODEINE.
13
Reports of Hepatic necrosis with CODEINE
0.1%
of all CODEINE reports
12
Deaths
4
Hospitalizations
How Dangerous Is Hepatic necrosis From CODEINE?
Of the 13 reports, 12 (92.3%) resulted in death, 4 (30.8%) required hospitalization.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which CODEINE Alternatives Have Lower Hepatic necrosis Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE