Does CODEINE Cause Hypercalcaemia? 567 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 567 reports of Hypercalcaemia have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 2.6% of all adverse event reports for CODEINE.
567
Reports of Hypercalcaemia with CODEINE
2.6%
of all CODEINE reports
11
Deaths
539
Hospitalizations
How Dangerous Is Hypercalcaemia From CODEINE?
Of the 567 reports, 11 (1.9%) resulted in death, 539 (95.1%) required hospitalization, and 20 (3.5%) were considered life-threatening.
Is Hypercalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 567 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Hypercalcaemia?
RITUXIMAB (857)
METHOTREXATE (803)
ADALIMUMAB (663)
TOCILIZUMAB (618)
ABATACEPT (612)
ETANERCEPT (602)
DENOSUMAB (599)
ALENDRONATE (594)
INFLIXIMAB (594)
LEFLUNOMIDE (585)
Which CODEINE Alternatives Have Lower Hypercalcaemia Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE