Hypercalcaemia: Which Medications Cause It? (8,674 Reports Across 511 Drugs)
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Hypercalcaemia has been reported as an adverse event with 511 different drugs in the FDA's FAERS database, with 8,674 total reports. 1,196 of these reports resulted in death.The drugs most commonly associated with Hypercalcaemia are RITUXIMAB, METHOTREXATE, and ADALIMUMAB.
8,674
Total Reports
511
Drugs Involved
1,196
Deaths
5,715
Hospitalizations
59.8 yrs
Average Patient Age
60.2% / 39.8%
Female / Male
Which Drugs Cause Hypercalcaemia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| RITUXIMAB | 857 | 0.5% | 78 | 699 | 38 |
| METHOTREXATE | 803 | 0.3% | 19 | 739 | 53 |
| ADALIMUMAB | 663 | 0.1% | 10 | 625 | 27 |
| TOCILIZUMAB | 618 | 0.6% | 7 | 589 | 23 |
| ABATACEPT | 612 | 0.5% | 1 | 588 | 23 |
| ETANERCEPT | 602 | 0.2% | 4 | 570 | 25 |
| DENOSUMAB | 599 | 0.4% | 60 | 288 | 18 |
| ALENDRONATE | 594 | 2.1% | 3 | 567 | 20 |
| INFLIXIMAB | 594 | 0.4% | 1 | 568 | 21 |
| LEFLUNOMIDE | 585 | 1.0% | 1 | 564 | 21 |
| CODEINE | 567 | 2.6% | 11 | 539 | 20 |
| HYDROXYCHLOROQUINE | 566 | 0.9% | 0 | 547 | 27 |
| SULFASALAZINE | 549 | 1.4% | 0 | 532 | 20 |
| CALCIUM | 530 | 3.4% | 21 | 406 | 56 |
| DEXAMETHASONE | 496 | 0.4% | 154 | 330 | 70 |
| LENALIDOMIDE | 496 | 0.1% | 126 | 351 | 49 |
| GOLD THIOMALATE | 355 | 7.9% | 0 | 347 | 19 |
| NIVOLUMAB | 324 | 0.4% | 89 | 259 | 35 |
| CALCITRIOL | 299 | 12.6% | 5 | 196 | 27 |
| PREDNISONE | 288 | 0.2% | 35 | 204 | 41 |