Does NIVOLUMAB Cause Hypercalcaemia? 324 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 324 reports of Hypercalcaemia have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.4% of all adverse event reports for NIVOLUMAB.
324
Reports of Hypercalcaemia with NIVOLUMAB
0.4%
of all NIVOLUMAB reports
89
Deaths
259
Hospitalizations
How Dangerous Is Hypercalcaemia From NIVOLUMAB?
Of the 324 reports, 89 (27.5%) resulted in death, 259 (79.9%) required hospitalization, and 35 (10.8%) were considered life-threatening.
Is Hypercalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 324 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Hypercalcaemia?
RITUXIMAB (857)
METHOTREXATE (803)
ADALIMUMAB (663)
TOCILIZUMAB (618)
ABATACEPT (612)
ETANERCEPT (602)
DENOSUMAB (599)
ALENDRONATE (594)
INFLIXIMAB (594)
LEFLUNOMIDE (585)
Which NIVOLUMAB Alternatives Have Lower Hypercalcaemia Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE