Does DENOSUMAB Cause Hypercalcaemia? 599 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 599 reports of Hypercalcaemia have been filed in association with DENOSUMAB (Bilprevda). This represents 0.4% of all adverse event reports for DENOSUMAB.
599
Reports of Hypercalcaemia with DENOSUMAB
0.4%
of all DENOSUMAB reports
60
Deaths
288
Hospitalizations
How Dangerous Is Hypercalcaemia From DENOSUMAB?
Of the 599 reports, 60 (10.0%) resulted in death, 288 (48.1%) required hospitalization, and 18 (3.0%) were considered life-threatening.
Is Hypercalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DENOSUMAB. However, 599 reports have been filed with the FAERS database.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Hypercalcaemia?
RITUXIMAB (857)
METHOTREXATE (803)
ADALIMUMAB (663)
TOCILIZUMAB (618)
ABATACEPT (612)
ETANERCEPT (602)
ALENDRONATE (594)
INFLIXIMAB (594)
LEFLUNOMIDE (585)
CODEINE (567)
Which DENOSUMAB Alternatives Have Lower Hypercalcaemia Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE