Does CODEINE Cause Osteoarthritis? 256 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 256 reports of Osteoarthritis have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 1.2% of all adverse event reports for CODEINE.
256
Reports of Osteoarthritis with CODEINE
1.2%
of all CODEINE reports
177
Deaths
178
Hospitalizations
How Dangerous Is Osteoarthritis From CODEINE?
Of the 256 reports, 177 (69.1%) resulted in death, 178 (69.5%) required hospitalization, and 146 (57.0%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 256 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
TOFACITINIB (2,831)
HYDROXYCHLOROQUINE (2,717)
Which CODEINE Alternatives Have Lower Osteoarthritis Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE