Does COLCHICINE Cause Hepatic necrosis? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hepatic necrosis have been filed in association with COLCHICINE (colchicine). This represents 0.2% of all adverse event reports for COLCHICINE.
14
Reports of Hepatic necrosis with COLCHICINE
0.2%
of all COLCHICINE reports
10
Deaths
13
Hospitalizations
How Dangerous Is Hepatic necrosis From COLCHICINE?
Of the 14 reports, 10 (71.4%) resulted in death, 13 (92.9%) required hospitalization, and 4 (28.6%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COLCHICINE. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does COLCHICINE Cause?
Diarrhoea (1,005)
Drug ineffective (943)
Off label use (900)
Toxicity to various agents (775)
Acute kidney injury (547)
Vomiting (447)
Nausea (421)
Abdominal pain (335)
Fatigue (314)
Overdose (302)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which COLCHICINE Alternatives Have Lower Hepatic necrosis Risk?
COLCHICINE vs COLCHICINE\DICYCLOMINE
COLCHICINE vs COLCHICINE\OPIUM\TIEMONIUM METHYLSULFATE
COLCHICINE vs COLESEVELAM
COLCHICINE vs COLESTIPOL
COLCHICINE vs COLISTIMETHATE