Does CYCLOPHOSPHAMIDE Cause Necrosis? 97 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 97 reports of Necrosis have been filed in association with CYCLOPHOSPHAMIDE (Cyclophosphamide). This represents 0.1% of all adverse event reports for CYCLOPHOSPHAMIDE.
97
Reports of Necrosis with CYCLOPHOSPHAMIDE
0.1%
of all CYCLOPHOSPHAMIDE reports
20
Deaths
54
Hospitalizations
How Dangerous Is Necrosis From CYCLOPHOSPHAMIDE?
Of the 97 reports, 20 (20.6%) resulted in death, 54 (55.7%) required hospitalization, and 13 (13.4%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
Yes, Necrosis is listed as a known adverse reaction in the official FDA drug label for CYCLOPHOSPHAMIDE.
What Other Side Effects Does CYCLOPHOSPHAMIDE Cause?
Off label use (12,578)
Febrile neutropenia (11,318)
Drug ineffective (8,142)
Neutropenia (7,352)
Disease progression (7,100)
Pyrexia (6,126)
Product use in unapproved indication (5,750)
Thrombocytopenia (4,669)
Pneumonia (4,595)
Nausea (4,561)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
DEXAMETHASONE (74)
Which CYCLOPHOSPHAMIDE Alternatives Have Lower Necrosis Risk?
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE FOR , USP
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\RITUXIMAB\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOSERINE
CYCLOPHOSPHAMIDE vs CYCLOSPORINE