Does TACROLIMUS Cause Necrosis? 120 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 120 reports of Necrosis have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.1% of all adverse event reports for TACROLIMUS.
120
Reports of Necrosis with TACROLIMUS
0.1%
of all TACROLIMUS reports
43
Deaths
85
Hospitalizations
How Dangerous Is Necrosis From TACROLIMUS?
Of the 120 reports, 43 (35.8%) resulted in death, 85 (70.8%) required hospitalization, and 19 (15.8%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
Yes, Necrosis is listed as a known adverse reaction in the official FDA drug label for TACROLIMUS.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
DEXAMETHASONE (74)
Which TACROLIMUS Alternatives Have Lower Necrosis Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB