Does CYCLOSPORINE Cause Osteonecrosis? 197 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 197 reports of Osteonecrosis have been filed in association with CYCLOSPORINE (Verkazia). This represents 0.3% of all adverse event reports for CYCLOSPORINE.
197
Reports of Osteonecrosis with CYCLOSPORINE
0.3%
of all CYCLOSPORINE reports
19
Deaths
87
Hospitalizations
How Dangerous Is Osteonecrosis From CYCLOSPORINE?
Of the 197 reports, 19 (9.6%) resulted in death, 87 (44.2%) required hospitalization, and 4 (2.0%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYCLOSPORINE. However, 197 reports have been filed with the FAERS database.
What Other Side Effects Does CYCLOSPORINE Cause?
Drug ineffective (11,172)
Off label use (6,860)
Eye irritation (5,806)
Product use in unapproved indication (5,019)
Condition aggravated (2,310)
Eye pain (2,197)
Drug intolerance (2,176)
Pneumonia (2,022)
Pyrexia (2,020)
Treatment failure (1,961)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which CYCLOSPORINE Alternatives Have Lower Osteonecrosis Risk?
CYCLOSPORINE vs CYCLOSPORINE A
CYCLOSPORINE vs CYMBALTA
CYCLOSPORINE vs CYNODON DACTYLON POLLEN
CYCLOSPORINE vs CYPROHEPTADINE
CYCLOSPORINE vs CYPROTERONE