Does DABRAFENIB Cause Hepatic failure? 52 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 52 reports of Hepatic failure have been filed in association with DABRAFENIB (Tafinlar). This represents 0.3% of all adverse event reports for DABRAFENIB.
52
Reports of Hepatic failure with DABRAFENIB
0.3%
of all DABRAFENIB reports
14
Deaths
29
Hospitalizations
How Dangerous Is Hepatic failure From DABRAFENIB?
Of the 52 reports, 14 (26.9%) resulted in death, 29 (55.8%) required hospitalization, and 10 (19.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DABRAFENIB. However, 52 reports have been filed with the FAERS database.
What Other Side Effects Does DABRAFENIB Cause?
Pyrexia (3,788)
Death (2,740)
Malignant neoplasm progression (1,667)
Fatigue (1,328)
Nausea (1,300)
Chills (1,235)
Rash (1,078)
Vomiting (907)
Diarrhoea (901)
Headache (697)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which DABRAFENIB Alternatives Have Lower Hepatic failure Risk?
DABRAFENIB vs DABRAFENIB\TRAMETINIB
DABRAFENIB vs DACARBAZINE
DABRAFENIB vs DACLATASVIR
DABRAFENIB vs DACLIZUMAB
DABRAFENIB vs DACOMITINIB