Does DABRAFENIB Cause Hypophysitis? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hypophysitis have been filed in association with DABRAFENIB (Tafinlar). This represents 0.1% of all adverse event reports for DABRAFENIB.
27
Reports of Hypophysitis with DABRAFENIB
0.1%
of all DABRAFENIB reports
3
Deaths
12
Hospitalizations
How Dangerous Is Hypophysitis From DABRAFENIB?
Of the 27 reports, 3 (11.1%) resulted in death, 12 (44.4%) required hospitalization, and 2 (7.4%) were considered life-threatening.
Is Hypophysitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DABRAFENIB. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does DABRAFENIB Cause?
Pyrexia (3,788)
Death (2,740)
Malignant neoplasm progression (1,667)
Fatigue (1,328)
Nausea (1,300)
Chills (1,235)
Rash (1,078)
Vomiting (907)
Diarrhoea (901)
Headache (697)
What Other Drugs Cause Hypophysitis?
IPILIMUMAB (981)
NIVOLUMAB (755)
PEMBROLIZUMAB (411)
CARBOPLATIN (144)
ATEZOLIZUMAB (125)
PACLITAXEL (110)
BEVACIZUMAB (61)
DURVALUMAB (60)
PEMETREXED (51)
CYCLOPHOSPHAMIDE (38)
Which DABRAFENIB Alternatives Have Lower Hypophysitis Risk?
DABRAFENIB vs DABRAFENIB\TRAMETINIB
DABRAFENIB vs DACARBAZINE
DABRAFENIB vs DACLATASVIR
DABRAFENIB vs DACLIZUMAB
DABRAFENIB vs DACOMITINIB