Does DACARBAZINE Cause Hepatic failure? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Hepatic failure have been filed in association with DACARBAZINE (Dacarbazine). This represents 0.4% of all adverse event reports for DACARBAZINE.
22
Reports of Hepatic failure with DACARBAZINE
0.4%
of all DACARBAZINE reports
10
Deaths
9
Hospitalizations
How Dangerous Is Hepatic failure From DACARBAZINE?
Of the 22 reports, 10 (45.5%) resulted in death, 9 (40.9%) required hospitalization, and 4 (18.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DACARBAZINE. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does DACARBAZINE Cause?
Febrile neutropenia (501)
Off label use (471)
Neutropenia (400)
Drug ineffective (261)
Pyrexia (245)
Neuropathy peripheral (239)
Product use in unapproved indication (219)
Disease progression (204)
Nausea (203)
Anaemia (186)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which DACARBAZINE Alternatives Have Lower Hepatic failure Risk?
DACARBAZINE vs DACLATASVIR
DACARBAZINE vs DACLIZUMAB
DACARBAZINE vs DACOMITINIB
DACARBAZINE vs DACTINOMYCIN
DACARBAZINE vs DALBAVANCIN