Does DACARBAZINE Cause Osteonecrosis? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Osteonecrosis have been filed in association with DACARBAZINE (Dacarbazine). This represents 0.3% of all adverse event reports for DACARBAZINE.
14
Reports of Osteonecrosis with DACARBAZINE
0.3%
of all DACARBAZINE reports
1
Deaths
2
Hospitalizations
How Dangerous Is Osteonecrosis From DACARBAZINE?
Of the 14 reports, 1 (7.1%) resulted in death, 2 (14.3%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DACARBAZINE. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does DACARBAZINE Cause?
Febrile neutropenia (501)
Off label use (471)
Neutropenia (400)
Drug ineffective (261)
Pyrexia (245)
Neuropathy peripheral (239)
Product use in unapproved indication (219)
Disease progression (204)
Nausea (203)
Anaemia (186)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which DACARBAZINE Alternatives Have Lower Osteonecrosis Risk?
DACARBAZINE vs DACLATASVIR
DACARBAZINE vs DACLIZUMAB
DACARBAZINE vs DACOMITINIB
DACARBAZINE vs DACTINOMYCIN
DACARBAZINE vs DALBAVANCIN