Does DARATUMUMAB Cause Hepatic failure? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Hepatic failure have been filed in association with DARATUMUMAB (DARZALEX). This represents 0.1% of all adverse event reports for DARATUMUMAB.
33
Reports of Hepatic failure with DARATUMUMAB
0.1%
of all DARATUMUMAB reports
17
Deaths
18
Hospitalizations
How Dangerous Is Hepatic failure From DARATUMUMAB?
Of the 33 reports, 17 (51.5%) resulted in death, 18 (54.5%) required hospitalization, and 7 (21.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for DARATUMUMAB.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which DARATUMUMAB Alternatives Have Lower Hepatic failure Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE