Does DEFERASIROX Cause Hyperammonaemic encephalopathy? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hyperammonaemic encephalopathy have been filed in association with DEFERASIROX (Deferasirox). This represents 0.1% of all adverse event reports for DEFERASIROX.
15
Reports of Hyperammonaemic encephalopathy with DEFERASIROX
0.1%
of all DEFERASIROX reports
0
Deaths
12
Hospitalizations
How Dangerous Is Hyperammonaemic encephalopathy From DEFERASIROX?
Of the 15 reports, 12 (80.0%) required hospitalization, and 10 (66.7%) were considered life-threatening.
Is Hyperammonaemic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERASIROX. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERASIROX Cause?
Death (1,583)
Diarrhoea (993)
Serum ferritin increased (732)
Haemoglobin decreased (615)
Pyrexia (607)
Malaise (605)
Nausea (603)
Sickle cell anaemia with crisis (570)
Vomiting (520)
Pneumonia (494)
What Other Drugs Cause Hyperammonaemic encephalopathy?
VALPROIC ACID (455)
FLUOROURACIL (156)
VALPROATE (120)
DIVALPROEX (119)
OXALIPLATIN (107)
TOPIRAMATE (101)
RISPERIDONE (96)
QUETIAPINE (91)
LEVETIRACETAM (71)
LEUCOVORIN (62)
Which DEFERASIROX Alternatives Have Lower Hyperammonaemic encephalopathy Risk?
DEFERASIROX vs DEFERIPRONE
DEFERASIROX vs DEFEROXAMINE
DEFERASIROX vs DEFIBROTIDE
DEFERASIROX vs DEFLAZACORT
DEFERASIROX vs DEGARELIX