Does DEFERASIROX Cause Polyneuropathy? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Polyneuropathy have been filed in association with DEFERASIROX (Deferasirox). This represents 0.1% of all adverse event reports for DEFERASIROX.
11
Reports of Polyneuropathy with DEFERASIROX
0.1%
of all DEFERASIROX reports
4
Deaths
11
Hospitalizations
How Dangerous Is Polyneuropathy From DEFERASIROX?
Of the 11 reports, 4 (36.4%) resulted in death, 11 (100.0%) required hospitalization, and 2 (18.2%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERASIROX. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERASIROX Cause?
Death (1,583)
Diarrhoea (993)
Serum ferritin increased (732)
Haemoglobin decreased (615)
Pyrexia (607)
Malaise (605)
Nausea (603)
Sickle cell anaemia with crisis (570)
Vomiting (520)
Pneumonia (494)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which DEFERASIROX Alternatives Have Lower Polyneuropathy Risk?
DEFERASIROX vs DEFERIPRONE
DEFERASIROX vs DEFEROXAMINE
DEFERASIROX vs DEFIBROTIDE
DEFERASIROX vs DEFLAZACORT
DEFERASIROX vs DEGARELIX