Does DENOSUMAB Cause Osteoarthritis? 568 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 568 reports of Osteoarthritis have been filed in association with DENOSUMAB (Bilprevda). This represents 0.4% of all adverse event reports for DENOSUMAB.
568
Reports of Osteoarthritis with DENOSUMAB
0.4%
of all DENOSUMAB reports
13
Deaths
92
Hospitalizations
How Dangerous Is Osteoarthritis From DENOSUMAB?
Of the 568 reports, 13 (2.3%) resulted in death, 92 (16.2%) required hospitalization, and 3 (0.5%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
Yes, Osteoarthritis is listed as a known adverse reaction in the official FDA drug label for DENOSUMAB.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
TOFACITINIB (2,831)
HYDROXYCHLOROQUINE (2,717)
Which DENOSUMAB Alternatives Have Lower Osteoarthritis Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE