Does DEXRAZOXANE Cause Encephalopathy? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Encephalopathy have been filed in association with DEXRAZOXANE (Dexrazoxane). This represents 0.5% of all adverse event reports for DEXRAZOXANE.
6
Reports of Encephalopathy with DEXRAZOXANE
0.5%
of all DEXRAZOXANE reports
3
Deaths
5
Hospitalizations
How Dangerous Is Encephalopathy From DEXRAZOXANE?
Of the 6 reports, 3 (50.0%) resulted in death, 5 (83.3%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEXRAZOXANE. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does DEXRAZOXANE Cause?
Febrile neutropenia (315)
Off label use (266)
Clostridium difficile colitis (91)
Cellulitis (84)
Product use in unapproved indication (84)
Pyrexia (81)
Fungal infection (74)
Bacterial infection (73)
Lymphoid tissue hypoplasia (72)
Lymphopenia (70)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which DEXRAZOXANE Alternatives Have Lower Encephalopathy Risk?
DEXRAZOXANE vs DEXTRAN 70\HYPROMELLOSE 2910
DEXRAZOXANE vs DEXTROAMPHETAMINE
DEXRAZOXANE vs DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE AND AMPHETAMINE
DEXRAZOXANE vs DEXTROMETHORPHAN
DEXRAZOXANE vs DEXTROMETHORPHAN HYDROBROMIDE