Does DISULFIRAM Cause Hepatic failure? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Hepatic failure have been filed in association with DISULFIRAM (Disulfiram). This represents 1.6% of all adverse event reports for DISULFIRAM.
12
Reports of Hepatic failure with DISULFIRAM
1.6%
of all DISULFIRAM reports
0
Deaths
11
Hospitalizations
How Dangerous Is Hepatic failure From DISULFIRAM?
Of the 12 reports, 11 (91.7%) required hospitalization, and 3 (25.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for DISULFIRAM.
What Other Side Effects Does DISULFIRAM Cause?
Off label use (107)
Fatigue (73)
Drug abuse (68)
Toxicity to various agents (64)
Drug-induced liver injury (46)
Drug interaction (44)
Drug ineffective (43)
Psychiatric symptom (42)
Intentional self-injury (37)
Nausea (33)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which DISULFIRAM Alternatives Have Lower Hepatic failure Risk?
DISULFIRAM vs DIVALPROEX
DISULFIRAM vs DOBUTAMINE
DISULFIRAM vs DOBUTAMINE\DOBUTAMINE
DISULFIRAM vs DOCETAXEL
DISULFIRAM vs DOCETAXEL ANHYDROUS