Does DISULFIRAM Cause Polyneuropathy? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Polyneuropathy have been filed in association with DISULFIRAM (Disulfiram). This represents 2.0% of all adverse event reports for DISULFIRAM.
15
Reports of Polyneuropathy with DISULFIRAM
2.0%
of all DISULFIRAM reports
1
Deaths
6
Hospitalizations
How Dangerous Is Polyneuropathy From DISULFIRAM?
Of the 15 reports, 1 (6.7%) resulted in death, 6 (40.0%) required hospitalization.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DISULFIRAM. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does DISULFIRAM Cause?
Off label use (107)
Fatigue (73)
Drug abuse (68)
Toxicity to various agents (64)
Drug-induced liver injury (46)
Drug interaction (44)
Drug ineffective (43)
Psychiatric symptom (42)
Intentional self-injury (37)
Nausea (33)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which DISULFIRAM Alternatives Have Lower Polyneuropathy Risk?
DISULFIRAM vs DIVALPROEX
DISULFIRAM vs DOBUTAMINE
DISULFIRAM vs DOBUTAMINE\DOBUTAMINE
DISULFIRAM vs DOCETAXEL
DISULFIRAM vs DOCETAXEL ANHYDROUS