Does DIVALPROEX Cause Spina bifida? 71 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 71 reports of Spina bifida have been filed in association with DIVALPROEX (Divalproex Sodium). This represents 0.6% of all adverse event reports for DIVALPROEX.
71
Reports of Spina bifida with DIVALPROEX
0.6%
of all DIVALPROEX reports
10
Deaths
2
Hospitalizations
How Dangerous Is Spina bifida From DIVALPROEX?
Of the 71 reports, 10 (14.1%) resulted in death, 2 (2.8%) required hospitalization, and 2 (2.8%) were considered life-threatening.
Is Spina bifida Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DIVALPROEX. However, 71 reports have been filed with the FAERS database.
What Other Side Effects Does DIVALPROEX Cause?
Drug ineffective (1,121)
Seizure (1,095)
Off label use (576)
Somnolence (545)
Drug interaction (540)
Nausea (526)
Weight increased (509)
Tremor (461)
Toxicity to various agents (452)
Vomiting (436)
What Other Drugs Cause Spina bifida?
OXYCODONE (268)
ACETAMINOPHEN\OXYCODONE (200)
ACETAMINOPHEN\HYDROCODONE (188)
HYDROMORPHONE (174)
MORPHINE (159)
LAMOTRIGINE (142)
TRAMADOL (136)
BUPRENORPHINE (107)
VALPROIC ACID (101)
HYDROCODONE (93)
Which DIVALPROEX Alternatives Have Lower Spina bifida Risk?
DIVALPROEX vs DOBUTAMINE
DIVALPROEX vs DOBUTAMINE\DOBUTAMINE
DIVALPROEX vs DOCETAXEL
DIVALPROEX vs DOCETAXEL ANHYDROUS
DIVALPROEX vs DOCETAXEL\DOCETAXEL ANHYDROUS