Does DOLUTEGRAVIR Cause Osteonecrosis? 59 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 59 reports of Osteonecrosis have been filed in association with DOLUTEGRAVIR (Juluca). This represents 0.6% of all adverse event reports for DOLUTEGRAVIR.
59
Reports of Osteonecrosis with DOLUTEGRAVIR
0.6%
of all DOLUTEGRAVIR reports
0
Deaths
25
Hospitalizations
How Dangerous Is Osteonecrosis From DOLUTEGRAVIR?
Of the 59 reports, 25 (42.4%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOLUTEGRAVIR. However, 59 reports have been filed with the FAERS database.
What Other Side Effects Does DOLUTEGRAVIR Cause?
Foetal exposure during pregnancy (1,036)
Exposure during pregnancy (776)
Virologic failure (770)
Pathogen resistance (586)
Maternal exposure during pregnancy (517)
Viral mutation identified (510)
Treatment failure (453)
Drug ineffective (447)
Off label use (413)
Blood hiv rna increased (410)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which DOLUTEGRAVIR Alternatives Have Lower Osteonecrosis Risk?
DOLUTEGRAVIR vs DOLUTEGRAVIR\LAMIVUDINE
DOLUTEGRAVIR vs DOLUTEGRAVIR\LAMIVUDINE\TENOFOVIR DISOPROXIL
DOLUTEGRAVIR vs DOLUTEGRAVIR\RILPIVIRINE
DOLUTEGRAVIR vs DOMPERIDONE
DOLUTEGRAVIR vs DOMPERIDONE\PANTOPRAZOLE