Does DORNASE ALFA Cause Multiple organ dysfunction syndrome? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Multiple organ dysfunction syndrome have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.1% of all adverse event reports for DORNASE ALFA.
6
Reports of Multiple organ dysfunction syndrome with DORNASE ALFA
0.1%
of all DORNASE ALFA reports
6
Deaths
4
Hospitalizations
How Dangerous Is Multiple organ dysfunction syndrome From DORNASE ALFA?
Of the 6 reports, 6 (100.0%) resulted in death, 4 (66.7%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Multiple organ dysfunction syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Multiple organ dysfunction syndrome?
TACROLIMUS (1,847)
CYCLOPHOSPHAMIDE (1,597)
MYCOPHENOLATE MOFETIL (1,566)
PREDNISONE (1,525)
DEXAMETHASONE (1,355)
METHOTREXATE (1,317)
METHYLPREDNISOLONE (1,278)
RITUXIMAB (1,188)
PREDNISOLONE (1,154)
CYCLOSPORINE (933)
Which DORNASE ALFA Alternatives Have Lower Multiple organ dysfunction syndrome Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68