Does METHOTREXATE Cause Multiple organ dysfunction syndrome? 1,317 Reports in FDA Database

Q: Does METHOTREXATE cause Multiple organ dysfunction syndrome?

1,317 reports of Multiple organ dysfunction syndrome have been filed with the FDA for METHOTREXATE, representing 0.5% of all METHOTREXATE adverse event reports.

Q: How dangerous is Multiple organ dysfunction syndrome from METHOTREXATE?

Of 1,317 reports, 1,104 (83.8%) resulted in death and 805 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 1,317 reports of Multiple organ dysfunction syndrome have been filed in association with METHOTREXATE (Methotrexate). This represents 0.5% of all adverse event reports for METHOTREXATE.

1,317

Reports of Multiple organ dysfunction syndrome with METHOTREXATE

0.5%

of all METHOTREXATE reports

1,104

Deaths

805

Hospitalizations

How Dangerous Is Multiple organ dysfunction syndrome From METHOTREXATE?

Of the 1,317 reports, 1,104 (83.8%) resulted in death, 805 (61.1%) required hospitalization, and 398 (30.2%) were considered life-threatening.

Is Multiple organ dysfunction syndrome Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,317 reports have been filed with the FAERS database.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Fatigue (19,885) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677)

What Other Drugs Cause Multiple organ dysfunction syndrome?

TACROLIMUS (1,847) CYCLOPHOSPHAMIDE (1,597) MYCOPHENOLATE MOFETIL (1,566) PREDNISONE (1,525) DEXAMETHASONE (1,355) METHYLPREDNISOLONE (1,278) RITUXIMAB (1,188) PREDNISOLONE (1,154) CYCLOSPORINE (933) VINCRISTINE (918)

Which METHOTREXATE Alternatives Have Lower Multiple organ dysfunction syndrome Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

METHOTREXATE Full Profile All Multiple organ dysfunction syndrome Reports All Drugs Causing Multiple organ dysfunction syndrome METHOTREXATE Demographics