Multiple organ dysfunction syndrome: Which Medications Cause It? (25,045 Reports Across 1,143 Drugs)
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Multiple organ dysfunction syndrome has been reported as an adverse event with 1,143 different drugs in the FDA's FAERS database, with 25,045 total reports. 19,978 of these reports resulted in death.The drugs most commonly associated with Multiple organ dysfunction syndrome are TACROLIMUS, CYCLOPHOSPHAMIDE, and MYCOPHENOLATE MOFETIL.
25,045
Total Reports
1,143
Drugs Involved
19,978
Deaths
14,559
Hospitalizations
53.4 yrs
Average Patient Age
45.6% / 54.4%
Female / Male
Which Drugs Cause Multiple organ dysfunction syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TACROLIMUS | 1,847 | 2.0% | 1,629 | 1,080 | 578 |
| CYCLOPHOSPHAMIDE | 1,597 | 1.2% | 1,424 | 730 | 347 |
| MYCOPHENOLATE MOFETIL | 1,566 | 2.1% | 1,366 | 864 | 460 |
| PREDNISONE | 1,525 | 1.0% | 1,336 | 934 | 507 |
| DEXAMETHASONE | 1,355 | 1.1% | 1,193 | 802 | 416 |
| METHOTREXATE | 1,317 | 0.5% | 1,104 | 805 | 398 |
| METHYLPREDNISOLONE | 1,278 | 2.0% | 1,168 | 783 | 443 |
| RITUXIMAB | 1,188 | 0.7% | 1,062 | 565 | 283 |
| PREDNISOLONE | 1,154 | 1.4% | 1,036 | 692 | 363 |
| CYCLOSPORINE | 933 | 1.4% | 832 | 399 | 208 |
| VINCRISTINE | 918 | 1.3% | 778 | 440 | 177 |
| ACETAMINOPHEN | 899 | 0.7% | 757 | 569 | 295 |
| METFORMIN | 808 | 0.9% | 507 | 624 | 423 |
| ETOPOSIDE | 807 | 1.5% | 684 | 351 | 199 |
| DOXORUBICIN | 800 | 1.0% | 709 | 392 | 185 |
| CYTARABINE | 786 | 1.8% | 661 | 387 | 175 |
| VANCOMYCIN | 728 | 2.2% | 553 | 463 | 257 |
| FLUDARABINE | 680 | 2.9% | 621 | 310 | 154 |
| MEROPENEM | 655 | 4.7% | 556 | 411 | 169 |
| CEFTRIAXONE | 550 | 2.8% | 492 | 340 | 241 |