Does DOXORUBICIN Cause Osteonecrosis? 200 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 200 reports of Osteonecrosis have been filed in association with DOXORUBICIN (Doxorubicin Hydrochloride). This represents 0.2% of all adverse event reports for DOXORUBICIN.
200
Reports of Osteonecrosis with DOXORUBICIN
0.2%
of all DOXORUBICIN reports
11
Deaths
30
Hospitalizations
How Dangerous Is Osteonecrosis From DOXORUBICIN?
Of the 200 reports, 11 (5.5%) resulted in death, 30 (15.0%) required hospitalization, and 3 (1.5%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOXORUBICIN. However, 200 reports have been filed with the FAERS database.
What Other Side Effects Does DOXORUBICIN Cause?
Febrile neutropenia (8,844)
Off label use (7,858)
Disease progression (6,165)
Neutropenia (5,891)
Drug ineffective (4,598)
Pyrexia (3,697)
Thrombocytopenia (3,638)
Anaemia (3,601)
Product use in unapproved indication (3,502)
Nausea (2,925)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which DOXORUBICIN Alternatives Have Lower Osteonecrosis Risk?
DOXORUBICIN vs DOXYCYCLINE
DOXORUBICIN vs DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYCYCLINE\DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYLAMINE
DOXORUBICIN vs DOXYLAMINE\PYRIDOXINE