Does EFAVIRENZ Cause Osteonecrosis? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Osteonecrosis have been filed in association with EFAVIRENZ (Efavirenz, Emtricitabine and Tenofovir Disoproxil Fumarate). This represents 0.2% of all adverse event reports for EFAVIRENZ.
19
Reports of Osteonecrosis with EFAVIRENZ
0.2%
of all EFAVIRENZ reports
0
Deaths
3
Hospitalizations
How Dangerous Is Osteonecrosis From EFAVIRENZ?
Of the 19 reports, 3 (15.8%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for EFAVIRENZ. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does EFAVIRENZ Cause?
Virologic failure (916)
Foetal exposure during pregnancy (701)
Drug resistance (654)
Drug interaction (645)
Viral mutation identified (641)
Depression (602)
Pathogen resistance (567)
Maternal exposure during pregnancy (478)
Treatment failure (390)
Immune reconstitution inflammatory syndrome (301)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which EFAVIRENZ Alternatives Have Lower Osteonecrosis Risk?
EFAVIRENZ vs EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL
EFAVIRENZ vs EFAVIRENZ\LAMIVUDINE\TENOFOVIR DISOPROXIL
EFAVIRENZ vs EFFEXOR
EFAVIRENZ vs EFFIENT
EFAVIRENZ vs EFGARTIGIMOD ALFA