EPLERENONE for Primary hyperaldosteronism: Side Effects & Safety Data
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There are 36 adverse event reports in the FDA FAERS database where EPLERENONE was used for Primary hyperaldosteronism.
Most Reported Side Effects for EPLERENONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Acute kidney injury | 570 | 15.3% | 34 | 481 |
| Hypotension | 398 | 10.7% | 24 | 312 |
| Dyspnoea | 395 | 10.6% | 25 | 287 |
| Cardiac failure | 338 | 9.1% | 38 | 261 |
| Oedema peripheral | 268 | 7.2% | 16 | 201 |
| Dizziness | 248 | 6.6% | 5 | 138 |
| Hyperkalaemia | 248 | 6.6% | 14 | 163 |
| Drug ineffective | 244 | 6.5% | 10 | 149 |
| Fatigue | 202 | 5.4% | 2 | 94 |
| Off label use | 188 | 5.0% | 7 | 93 |
| Nausea | 170 | 4.6% | 10 | 107 |
| Diarrhoea | 158 | 4.2% | 4 | 78 |
| Bradycardia | 157 | 4.2% | 0 | 112 |
| Condition aggravated | 147 | 3.9% | 8 | 105 |
| Renal impairment | 140 | 3.8% | 24 | 84 |
Other Indications for EPLERENONE
Product used for unknown indication (1,445)
Cardiac failure (504)
Hypertension (293)
Cardiac failure chronic (131)
Cardiac failure congestive (64)
Myocardial ischaemia (61)
Diuretic therapy (38)
Congestive cardiomyopathy (36)
Hyperaldosteronism (26)
Cardiomyopathy (24)