Does EPLERENONE Cause Renal impairment? 140 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 140 reports of Renal impairment have been filed in association with EPLERENONE (Inspra). This represents 3.8% of all adverse event reports for EPLERENONE.
140
Reports of Renal impairment with EPLERENONE
3.8%
of all EPLERENONE reports
24
Deaths
84
Hospitalizations
How Dangerous Is Renal impairment From EPLERENONE?
Of the 140 reports, 24 (17.1%) resulted in death, 84 (60.0%) required hospitalization, and 10 (7.1%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for EPLERENONE. However, 140 reports have been filed with the FAERS database.
What Other Side Effects Does EPLERENONE Cause?
Acute kidney injury (570)
Hypotension (398)
Dyspnoea (395)
Cardiac failure (338)
Oedema peripheral (268)
Dizziness (248)
Hyperkalaemia (248)
Drug ineffective (244)
Fatigue (202)
Off label use (188)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which EPLERENONE Alternatives Have Lower Renal impairment Risk?
EPLERENONE vs EPLONTERSEN
EPLERENONE vs EPOETIN ALFA-EPBX
EPLERENONE vs EPOGEN
EPLERENONE vs EPOPROSTENOL
EPLERENONE vs EPTIFIBATIDE