Does ESTRADIOL Cause Discomfort? 249 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 249 reports of Discomfort have been filed in association with ESTRADIOL (Estradiol). This represents 0.8% of all adverse event reports for ESTRADIOL.
249
Reports of Discomfort with ESTRADIOL
0.8%
of all ESTRADIOL reports
5
Deaths
17
Hospitalizations
How Dangerous Is Discomfort From ESTRADIOL?
Of the 249 reports, 5 (2.0%) resulted in death, 17 (6.8%) required hospitalization, and 5 (2.0%) were considered life-threatening.
Is Discomfort Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ESTRADIOL. However, 249 reports have been filed with the FAERS database.
What Other Side Effects Does ESTRADIOL Cause?
Product adhesion issue (4,774)
Drug ineffective (4,010)
Off label use (3,238)
Hot flush (2,264)
Wrong technique in product usage process (1,871)
Product quality issue (1,671)
Headache (1,504)
No adverse event (1,493)
Application site pruritus (1,181)
Application site erythema (1,117)
What Other Drugs Cause Discomfort?
ADALIMUMAB (6,569)
METHOTREXATE (5,760)
PREDNISONE (5,288)
INFLIXIMAB (5,209)
ETANERCEPT (5,185)
ABATACEPT (5,180)
RITUXIMAB (5,143)
DICLOFENAC (5,111)
TOCILIZUMAB (5,111)
LEFLUNOMIDE (5,037)
Which ESTRADIOL Alternatives Have Lower Discomfort Risk?
ESTRADIOL vs ESTRADIOL CYPIONATE
ESTRADIOL vs ESTRADIOL\LEVONORGESTREL
ESTRADIOL vs ESTRADIOL\NORETHINDRONE
ESTRADIOL vs ESTRADIOL\NORETHINDRONE\RELUGOLIX
ESTRADIOL vs ESTRADIOL\PROGESTERONE