Discomfort: Which Medications Cause It? (48,896 Reports Across 1,221 Drugs)
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Discomfort has been reported as an adverse event with 1,221 different drugs in the FDA's FAERS database, with 48,896 total reports. 2,407 of these reports resulted in death.The drugs most commonly associated with Discomfort are ADALIMUMAB, METHOTREXATE, and PREDNISONE.
48,896
Total Reports
1,221
Drugs Involved
2,407
Deaths
9,763
Hospitalizations
51.9 yrs
Average Patient Age
71.7% / 28.3%
Female / Male
Which Drugs Cause Discomfort Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 6,569 | 1.3% | 1,217 | 2,131 | 1,619 |
| METHOTREXATE | 5,760 | 2.3% | 1,187 | 1,963 | 1,671 |
| PREDNISONE | 5,288 | 3.3% | 1,159 | 1,881 | 1,614 |
| INFLIXIMAB | 5,209 | 3.7% | 1,118 | 1,720 | 1,557 |
| ETANERCEPT | 5,185 | 1.5% | 976 | 1,522 | 1,298 |
| ABATACEPT | 5,180 | 4.5% | 1,085 | 1,726 | 1,630 |
| RITUXIMAB | 5,143 | 2.9% | 1,190 | 1,918 | 1,636 |
| DICLOFENAC | 5,111 | 5.9% | 1,257 | 1,785 | 1,597 |
| TOCILIZUMAB | 5,111 | 5.2% | 1,221 | 1,794 | 1,570 |
| LEFLUNOMIDE | 5,037 | 8.9% | 1,132 | 1,813 | 1,677 |
| FOLIC ACID | 5,017 | 21.9% | 1,154 | 1,764 | 1,580 |
| CERTOLIZUMAB PEGOL | 4,960 | 5.0% | 1,149 | 1,631 | 1,540 |
| CETIRIZINE | 4,918 | 10.3% | 1,169 | 1,689 | 1,584 |
| HYDROXYCHLOROQUINE | 4,890 | 7.3% | 1,121 | 1,668 | 1,517 |
| GOLIMUMAB | 4,839 | 7.0% | 1,113 | 1,572 | 1,495 |
| DESOXIMETASONE | 4,829 | 41.5% | 1,155 | 1,629 | 1,567 |
| ALENDRONATE | 4,802 | 17.2% | 1,180 | 1,705 | 1,604 |
| SULFASALAZINE | 4,725 | 11.8% | 1,099 | 1,611 | 1,520 |
| TOFACITINIB | 4,629 | 3.0% | 1,009 | 1,536 | 1,434 |
| PSEUDOEPHEDRINE | 4,209 | 32.2% | 1,050 | 1,544 | 1,468 |