Does METHOTREXATE Cause Discomfort? 5,760 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5,760 reports of Discomfort have been filed in association with METHOTREXATE (Methotrexate). This represents 2.3% of all adverse event reports for METHOTREXATE.
5,760
Reports of Discomfort with METHOTREXATE
2.3%
of all METHOTREXATE reports
1,187
Deaths
1,963
Hospitalizations
How Dangerous Is Discomfort From METHOTREXATE?
Of the 5,760 reports, 1,187 (20.6%) resulted in death, 1,963 (34.1%) required hospitalization, and 1,671 (29.0%) were considered life-threatening.
Is Discomfort Listed in the Official Label?
Yes, Discomfort is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Discomfort?
ADALIMUMAB (6,569)
PREDNISONE (5,288)
INFLIXIMAB (5,209)
ETANERCEPT (5,185)
ABATACEPT (5,180)
RITUXIMAB (5,143)
DICLOFENAC (5,111)
TOCILIZUMAB (5,111)
LEFLUNOMIDE (5,037)
FOLIC ACID (5,017)
Which METHOTREXATE Alternatives Have Lower Discomfort Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA