Does ETOPOSIDE Cause Hepatosplenomegaly? 69 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 69 reports of Hepatosplenomegaly have been filed in association with ETOPOSIDE (Avopef). This represents 0.1% of all adverse event reports for ETOPOSIDE.
69
Reports of Hepatosplenomegaly with ETOPOSIDE
0.1%
of all ETOPOSIDE reports
35
Deaths
25
Hospitalizations
How Dangerous Is Hepatosplenomegaly From ETOPOSIDE?
Of the 69 reports, 35 (50.7%) resulted in death, 25 (36.2%) required hospitalization, and 13 (18.8%) were considered life-threatening.
Is Hepatosplenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ETOPOSIDE. However, 69 reports have been filed with the FAERS database.
What Other Side Effects Does ETOPOSIDE Cause?
Off label use (6,495)
Febrile neutropenia (5,966)
Disease progression (3,776)
Drug ineffective (3,687)
Neutropenia (3,641)
Thrombocytopenia (3,085)
Product use in unapproved indication (2,774)
Anaemia (2,586)
Pyrexia (2,453)
Sepsis (2,211)
What Other Drugs Cause Hepatosplenomegaly?
METHOTREXATE (149)
PREDNISONE (91)
CYCLOPHOSPHAMIDE (87)
RITUXIMAB (87)
VINCRISTINE (81)
DEXAMETHASONE (80)
PREDNISOLONE (72)
TACROLIMUS (71)
RUXOLITINIB (61)
CYCLOSPORINE (59)
Which ETOPOSIDE Alternatives Have Lower Hepatosplenomegaly Risk?
ETOPOSIDE vs ETORICOXIB
ETOPOSIDE vs ETRASIMOD ARGININE
ETOPOSIDE vs ETRAVIRINE
ETOPOSIDE vs EUCALYPTOL\MENTHOL\METHYL SALICYLATE\THYMOL
ETOPOSIDE vs EVEROLIMUS