Does RITUXIMAB Cause Hepatosplenomegaly? 87 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 87 reports of Hepatosplenomegaly have been filed in association with RITUXIMAB (Rituxan). This represents 0.1% of all adverse event reports for RITUXIMAB.
87
Reports of Hepatosplenomegaly with RITUXIMAB
0.1%
of all RITUXIMAB reports
22
Deaths
31
Hospitalizations
How Dangerous Is Hepatosplenomegaly From RITUXIMAB?
Of the 87 reports, 22 (25.3%) resulted in death, 31 (35.6%) required hospitalization, and 18 (20.7%) were considered life-threatening.
Is Hepatosplenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 87 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Hepatosplenomegaly?
METHOTREXATE (149)
PREDNISONE (91)
CYCLOPHOSPHAMIDE (87)
VINCRISTINE (81)
DEXAMETHASONE (80)
PREDNISOLONE (72)
TACROLIMUS (71)
ETOPOSIDE (69)
RUXOLITINIB (61)
CYCLOSPORINE (59)
Which RITUXIMAB Alternatives Have Lower Hepatosplenomegaly Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE