Does FILGRASTIM Cause Aplasia? 37 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 37 reports of Aplasia have been filed in association with FILGRASTIM (NYPOZI txid). This represents 0.3% of all adverse event reports for FILGRASTIM.
37
Reports of Aplasia with FILGRASTIM
0.3%
of all FILGRASTIM reports
9
Deaths
17
Hospitalizations
How Dangerous Is Aplasia From FILGRASTIM?
Of the 37 reports, 9 (24.3%) resulted in death, 17 (45.9%) required hospitalization, and 8 (21.6%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FILGRASTIM. However, 37 reports have been filed with the FAERS database.
What Other Side Effects Does FILGRASTIM Cause?
Off label use (1,930)
Febrile neutropenia (1,570)
Neutropenia (1,431)
Death (1,213)
Pyrexia (1,085)
Diarrhoea (739)
Nausea (718)
Bone pain (706)
Thrombocytopenia (697)
Anaemia (626)
What Other Drugs Cause Aplasia?
CYTARABINE (229)
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
Which FILGRASTIM Alternatives Have Lower Aplasia Risk?
FILGRASTIM vs FILGRASTIM-AAFI
FILGRASTIM vs FILGRASTIM-SNDZ
FILGRASTIM vs FINASTERIDE
FILGRASTIM vs FINASTERIDE\TAMSULOSIN
FILGRASTIM vs FINERENONE